The Amazing Spider-Man #15 (1964)

In this famous issue of The Amazing Spider-Man, our hero finds himself in a battle against not one, but two of his enemies. Spider-Man unwittingly lets the Chameleon escape and soon teams up with Kraven the Hunter. J. Jonah Jameson is quick to report on Kraven's arrival, but things take a nasty turn when Kraven injects Spider-Man with a potion that drastically weakens him. The result is a dramatic battle between the two adversaries, with Spidey eventually coming out victorious. It's a classic storyline that showcases Spider-Man's resourcefulness and resilience, even when facing overwhelming odds. If you're a collector, this is definitely a comic book that you'll want to add to your collection!